When using Microsoft Application Virtualization (SoftGrid) in a Citrix Presentation Server environment, you may run in to issues when applications use iexplorer.exe as a help subsystem. This issue is only prevalent in Citrix ICA connections - not RDP connections. The reason for this behavior has to do with Citrix content redirection. Fortunately, Aaron Parker has a solution to this issue. By adding the following to you OSD file, you can correct this behavior:

<REGISTRY>
<REGKEY HIVE=”HKCR” KEY=”HTTP\shell\open\command”>
<REGVALUE REGTYPE=”REG_SZ” NAME=”">”C:\Program Files\Internet Explorer\IEXPLORE.EXE” %1</REGVALUE>
</REGKEY>
</REGISTRY>

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